Challenges in Translation from Models to Humans in Fragile X Syndrome: The mGluR Story

Time: 8:00 am
day: Day Two

Details:

  • Initial attempts to translate the mGluR theory to adults with FXS – flaws and problems with interpreting results
  • Effects of AFQ056 (mGluR NAM) on language learning trial in young children with FXS – a trial designed to answer questions remaining from initial mGluR NAM trials
  • Approaches to more effectively determine when pre-clinical work in animal models will translate to humans – need to save time and resources during translation in fragile X and NDDs

Speakers: